Andrew Huberman· PhD
although it also tends to constrict blood vessels in many locations in the body.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
although it also tends to constrict blood vessels in many locations in the body.
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I mean nicotine is a vasoconstrictor and it raises blood pressure so that's basically stress on the system chronic stress
These effects are driven largely by nicotine’s activation of the sympathetic nervous system, which promotes vasoconstriction and impairs endothelial function.
More concerning is nicotine’s effect on arterial stiffness, which is a marker strongly associated with long-term cardiovascular disease risk.