Saturated fats from sources like butter, milk, eggs, and meat may raise LDL cholesterol, but this rise may not be pathological and could be a regulatory response to maintain cell membrane fluidity.

“so your APO B goes up your LDL goes up when you eat saturated fat but is that pathological I would say no that's not pathological that's just your body responding to the changes in your fat intake to keep the membranes fluid”

“the more saturated fat that I eat my LDL goes up maybe 10 to 15% when I'm eating Max saturated fat in my diet and this is just normal human physiology there's something called a homeoviscous model of adaptation that I won't get into in this podcast but I believe that the membranes of our cells probably shift in relationship to our fat composition and when we're eating more saturated fat the body has to make changes in the membranes to keep them at a certain level of fluidity and that requires LDL to go up a little bit to move cholesterol into the membranes of our cells”