Preventing atherosclerotic cardiovascular disease requires reducing apoB particles, protecting the endothelium, and managing inflammation.

“atherosclerosis atherogenesis is a multi-complex multifactorial disease and that's why even when Peter and I if we consult on a case and we realize in this person we have to beat up able B and get their particle numbers to a more physiologic range we don't stop once we do that we examine in great detail for other things that might be injuring the endothelium or the arterial wall and see are any of those treatable or so so we're getting a little bit smarter on lipoproteins but there certainly is more to it than just particle number”