Paul Saladino· MD
so they said most of the studies that are done on LDL cholesterol and show that it's not the cause or it might be the cause or it's not you know it's questionable are usually done on like a small subset of studies and they don't look at the totality of evidence so Brian ference said and his group said let's just look at every single study that's ever been done on cholesterol don't take anything out don't exclude studies don't cherry pick studies don't do anything look at every single study ever been done so they ended up with 20 million person years of follow-up they had so for example what does that mean if you have one million people and you follow them around for 20 years that's 20 million year person years of follow-up if you have uh two million people and you follow them around for 10 years that's also 20 million person years of follow-up so they wanted to look at every single study that has ever been done and that's what they did and they looked at mendelian randomization studies they looked at randomized control studies cohort studies in you know genetic studies pretty much anything you can imagine epidemiological studies like they looked at pretty much every study that's ever been done like I said the totality of evidence and they found that without question no matter how you measure it the higher the LDL cholesterol the more likely you are to have atherosclerosis heart attack Strokes death mortality from cardiovascular disease and non-cardiovascular disease