High LDL cholesterol may be less concerning for lipid-lowering therapy if a person has a zero Calcium Score (CAC).

“if you have high LDL doesn't matter what the context is whether you're primary prevention secondary prevention whether there's uh whether there's been a you know a stent placed Etc all of those sorts of things I can say that with the doctors that I'm working with right now they seem to interestingly be correlating a bit more themselves into the position that if you have high LDL there's a lot more recent data that if you have a zero CAC that it's probably not as meaningful — to take steps to lowering it”