Tlr4 activation increases nitric oxide production, a free radical that attacks tissues and generates toxic aldehydes contributing to cardiovascular disease.

“just the presence of endotoxin and by another senotoxin but any bacteria will probably trigger a similar thing the the reaction the inflammation the reaction from like a bacterial presence in the bloodstream very closely it's not identical to endotoxin in the bloodstream um and then um what else oh yeah I wanted to say so what happens we need a lot of fat well typically tryptophan when it's floating around in the bloodstream is is attached to something called albumin but free fatty acids and only free fatty acids are capable of displacing tryptophan from the albumin and now you have a lot of free-floating triple fam and then it becomes a competition between the free floating tryptophan and the other large neutral amino acids BCAA tyrogen phenomena to get into the brain now if you've eaten some food in this amount of protein in it then maybe these these other amino acids will outcompete the cube of them but if you let's say if you're”