The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
yeah that's one of the ways that the egg could be can be deranged and indeed the body can recognize the the peroxide issue with the oxidized lipids I should say directly as well and can actually was to that directly yeah so you know both of those things of pro-inflammatory
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so the when you get L linolic acid in the LDL particle and it oxidizes it damage the apop which is the protein in the LDL particle and that is one of the key initiating steps driving the the activation of the endothelial cells and also the immune Activation
Endothelial cells oxidize LDL forming linoleic acid hydroproxides. So when you're getting these oxidized LDL, it's usually from linoleic acid hydropoxides or oxidized linoleic acid.
So the when you get linoleic acid in the LDL particle and it oxidizes it damaged the apo which is the protein in the LDL particle and that is one of the key initiating steps driving the the activation of the endothelial cells and also the immune activation.
apob enriched or apob containing lipoproteins enriched in linolic acid are much more damaging to the endothelium than those that have lower populations of linolic acid