High HDL-C levels do not directly correlate with a reduced risk of cardiovascular disease.

“High HDL is not uniformly associated with protection and there's certain circumstances where that's true especially if it's extremely high perhaps we'll get back to this but there's a fair amount of evidence now including a recent paper that individuals of African ancestry who tend to have iron hdls anyway that the high hdls are not as protective or maybe not even HCL is that well associated with risk”