Paul Saladino· MD
Increasing the n-6 PUFA LA from safflower oil and safflower polyunsaturated margarine increased rates of death from cardiovascular disease, coronary heart disease, and all cause mortality.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Increasing the n-6 PUFA LA from safflower oil and safflower polyunsaturated margarine increased rates of death from cardiovascular disease, coronary heart disease, and all cause mortality.
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𝐌𝐨𝐫𝐞 𝐏𝐔𝐅𝐀 = 𝐦𝐨𝐫𝐞 𝐜𝐚𝐫𝐝𝐢𝐚𝐜 𝐞𝐯𝐞𝐧𝐭𝐬.
the result of this trial was that increasing omega-6 poly unrated fats from safflower oil and safflower oil polyunsaturated margarin increase the rates of death from cardiovascular disease coronary heart disease and all cause mortality