Proton pump inhibitors are associated with an increased risk of ischemic stroke and myocardial infarction, particularly with long-term use at high doses. — Whalespan
Proton pump inhibitors are associated with an increased risk of ischemic stroke and myocardial infarction, particularly with long-term use at high doses.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“long-term use of proton pump inhibitors dose dependent relationship associated risk of ischemic stroke in myocardial infarction proton pump inhibitors inhibit the production as we're talking about they're gonna decrease the nitric oxide they're used in the gut they're used in the stomach when we get excess acid production and use of PP is was associated with increased risks of first-time ischemic stroke and MI particularly among long-term users at high doses”