Peter Attia· MD
the neuron makes something called 24s hydroxy cholesterol for those of you who've listened to our first podcast you know cholesterol at one end has a hydroxy group that's what makes it somewhat water soluble but the other end of the cholesterol molecule has no hydroxy or it's all lipids but if we could stick another hydroxy group on the taale of the cholesterol molecule that has a hydroxy group at both ends it actually becomes a rare hydrophilic lipid it's a lipid that's soluble in water and it has no trouble passing through the bloodb brain barrier once it enters the bloodb brain barrier it's in plasma and it either rapidly binds to albumin or to any lipoprotein that's passing by and both the albumin or the lipoprotein brings that oxysterol to the liver which converts it to a bile acid and excretes it