Paul Saladino· MD
the LP a genetically determined you've got a high level or you have a low level and not a huge amount you can do about it
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the LP a genetically determined you've got a high level or you have a low level and not a huge amount you can do about it
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And it's one of those things that's not going to get picked up on your traditional cholesterol panel. Quick side note is, you know, if you're quote eating healthy and exercising and you still have a high LDL-C and you don't have access to the particle count, well, part of that LDL-C is going to be mis- calculating it as LPA. It's going to and you're not going to be able to do anything from a nutritional standpoint to be lowering that LDL-C at that point.
lipoprotein little A is the number one genetically inherited lipoprotein that increases the risk of early cardiovascular disease.