Neurons rely heavily on calcium regulation for communication, and calcium becomes dysregulated after traumatic brain injury, impacting cellular energy production.

“the reason is that neurons nerve cells rely very heavily on the regulation of calcium in order to generate those Action potentials to communicate with one another so it doesn't matter if it's a motor neuron a sensory neuron or a modulatory neuron they all generate Action potentials or something similar to it and calcium is important for that process calcium becomes dysregulated after traumatic brain injury in a number of different ways in particular in ways that impact the energy production systems of cells that are related to ATP adenosine triphosphate”