Andrew Huberman· PhD
In other words, having adequate levels of HDL is good, because it allows fats to be delivered to the tissues that manufactured testosterone, estrogen, cortisol in healthy levels and the liver.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
In other words, having adequate levels of HDL is good, because it allows fats to be delivered to the tissues that manufactured testosterone, estrogen, cortisol in healthy levels and the liver.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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You want healthy levels of HDL, and you want low levels of LDL, because if you have ovaries it will allow the fats that need to get to the ovary to produce estrogen, to get there. And if you have testes, it will allow the fats and the cholesterol molecules that you need in order to manufacture testosterone to get to the testes. As well, in order to have proper adrenal function and proper liver function, you want HDL and LDL in the healthy correct levels.