Disulfide bonds are involved in the polymerization of Von Willebrand Factor, which can trap platelets and cause white clots, potentially leading to thrombosis.

“this is also the main reason why we get thrombosis of platelets so pulmonary artery if you have the endothelial lining which makes sure that the red blood cells as they're going through the pulmonary artery are not causing clots if those if that endothelial lining would become damaged it would release underneath it and expose a huge collection of something called Von willbrand Factor Von willbrand factor is a monomer but it quickly becomes a polymer and the way it does that is in forming SS bonds so that's a a quick pull ization then of course the next step that happens is that these polymers will then trap platelets and cause them to Clump and you will get something called a white clot”