The United States is notably stubborn in its guidelines regarding ApoB measurement and discussion for cardiovascular risk assessment compared to Europe and Canada.

“the european guidelines the canadian guidelines are in line with the available evidence and the united states guidelines are you know just 40 years out of date”

“so some some guidelines uh like the american heart association guidelines uh which are um probably the less favorable for lpa measurement they'll tell you to measure i don't remember exactly but in patients with atherosclerotic cardiovascular disease or with a family history of atrocious cardiovascular disease in patients with familial hypercholesterolemia or in patients with aortic valve stenosis”