Paul Saladino· MD
what we are doing is using data from people who have high LDL s in the setting of insulin resistance or familial hypercholesterolemia and we are conflating that data as a predictor for these people with high LDL particle number
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
what we are doing is using data from people who have high LDL s in the setting of insulin resistance or familial hypercholesterolemia and we are conflating that data as a predictor for these people with high LDL particle number
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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these are divergent phenotypes and yet we're we're sort of lumping them all into the same thing and saying this is a risk for people