Paul Saladino· MD
beta-hydroxybutyrate can be used as fuel by the colonic and taro sites and so you don't need butyrate I talked about this Alain on the podcast you don't need butyrate for your colonic epithelial cells to be healthy
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
beta-hydroxybutyrate can be used as fuel by the colonic and taro sites and so you don't need butyrate I talked about this Alain on the podcast you don't need butyrate for your colonic epithelial cells to be healthy
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there have actually been studies done comparing vegetable and plant-based diets and carnivore diets and looking at the amount of short chain fatty acids and the carnivore diet you still make short chain fatty-acids you make different short chain fatty acids but the colonic epithelial cells which rely on those short chain fatty acids can use whatever they can use isobutyl a just as well as butyrate