Bryan Johnson· Author
both coffees lowered inflammation, caffeine drove it further down (IL6, IL10) > decaf raised systemic inflammation markers (hs-CRP, TNF-alpha)
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
both coffees lowered inflammation, caffeine drove it further down (IL6, IL10) > decaf raised systemic inflammation markers (hs-CRP, TNF-alpha)
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
on inflammation: caffeinated lowered IL6 and IL10, decaf raised CRP and TNF-alpha. The net inflammation story is split, not uniformly down.