Andrew Huberman· PhD
And actually the lactate system is its own form of fuel for the brain.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And actually the lactate system is its own form of fuel for the brain.
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give people • tests of standard cognitive tests then they exercise and build up their lactate they score better then they recover their lactate comes down they go back to their basil scores
Lactate, produced by muscles during intense exertion, transitions from a mere energy byproduct to a neuro-enhancing elixir, fueling both our physical and cognitive engines during and after a workout.
Lactate is crucial in elevating BDNF levels, which is one reason why vigorous exercise provides a notable BDNF boost when compared to lower-intensity and longer-duration training.
lactates being generated and it's it's it's crossing the blood-brain barrier and getting the brain i don't know if there's a reason for that i mean your astrocytes make lactate right they're highly glycolytic in fact mostly i think they're using using glucose to make lactate right that's shuttled into neurons and used as a very um easily used uh oxidizable source of energy but also it acts as a singly molecule and it's affecting bdnf and other things
So, during exercise the brain consumes it more than glucose. So, it actually, you know, you have both of them there, it'll go for the lactate over the glucose.
we know that lactate generated from exercise particularly as you get into that vigorous type of exercise that it does get into the brain there's actually human studies showing that gets into the brain and we know it's a signaling molecule for brain drive neurotrphic factor very important growth factor for brain health to grow new neurons to, you know, improve the neuroplasticity of the brain.