Psychedelic experiences can alter the models individuals hold of reality, including the sense of self.

“I mentioned earlier that these experiences seems to alter the models we hold of reality and I think the self is the biggest model that I am a thing that's separate from other things and that's I am defined by certain I have a certain personality and like I'm a smoker that's having a hard time quitting or I'm a depressed person that you know views myself as a failure and all of these things those are models too.”