The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Emerging research links vascular dysfunction to cognitive decline in aging & dementia. Reduced blood flow and blood-brain barrier breakdown may play a key role—and could even be causally connected.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and that is where vascular dysfunction particularly the blood vessels and capillaries that are lining the blood-brain barrier seems to be a really really early event that is common between all types of dementia and between Type 2 diabetes and apoe4
so the blood-brain barrier and and maintaining that Integrity is very important and both apoe4 and type 2 diabetes lead to permeability of that
based early vascular problems and we need to fix that to make sure that the brain doesn't develops and function normally to avoid dementia per se