Dopamine, norepinephrine, serotonin, and acetylcholine regulate the coordination of task-directed and default mode networks.

“So I think it's an important study to highlight because it really underscores the fact that something else is going on and that something else has everything to do with this ability to coordinate these tasks directed networks, and to coordinate that in the proper way with that default mode network and that is a process as you now know, that's regulated exquisitely by certain neurochemicals and in particular the neurochemicals, dopamine, norepinephrine and serotonin, and a fourth one I'd like to throw into the mix, which is acetylcholine, which is very vital for cognitive focus.”