Mitochondrial dysfunction is a central cause of long COVID symptoms, including fatigue and shortness of breath.

“the thing that gets them covid is the thing that keeps them actually having long so there was a study that was done looking at metabolism and they showed it was uh one of these plots where they looked at up regulation and down regulation of metabolism in the mitochondria and they looked at the enzymes of glycolysis if you can remember back all those enzymes and they looked at the enzymes of beta oxidation so fatty acid basically oxidation and it was pretty well shown that there was a significant downregulation in people with long covid versus people who had covid that didn't have long covid that had a downregulation in beta oxidation so they are they were not able to very well utilize and metabolize fatty acids in the mitochondria”