Andrew Huberman· PhD
Well, it's a pretty impressive nootropic to be honest.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Well, it's a pretty impressive nootropic to be honest.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Appetite suppressant and also increases focus. The problem is it often arrives in a delivery device that can kill you. But nicotine itself is a powerful agent. It also can offset age-related cognitive decline not entirely, but it makes the brain work better.
we know that nicotine Vaped smoked dipped or snuffed or these little Zin pouches or taken in capsule form does improve cognitive performance
yeah there's some evidence that keeping levels of neuromodulators like dopamine acetylcholine elevated despite the increases in blood pressure that are caused by consuming nicotine May indeed offset Parkinson's and Alzheimer's I'm not telling you this as a clinical trial I'm telling you this as anic data
there is a nice body of work to support the idea that nicotine delivered in any number of different forms can improve cognitive function to some extent
"...it does do something for those whose cognitive function is already impaired."
it's going to be acetylcholine bonding to nicotinic receptors I see we're not making nicotine we're not just binding so this is a this is a nicotinic acetylcholine receptorite of which there are at least seven and probably like 14 subtypes but — so right they're called nicotinic receptors in an annoying way in the same way that cannabinoid receptors are called cannabinoid receptors but then everyone thinks oh you know those receptors are there so because we're supposed to smoke pot or those receptors are there because we're supposed to ingest nicotine no the drugs that's right right exactly receptor was named after the drug and so the important thing to know is that whether or not it's basal forebrain or predunculopontine nucleus or a locust ceruleus that at least in the brain because we're not talking about muscle where acetylcholine does something else via nicotinic receptors there in general it just tends to be a signal to noise enhancer
we know that nicotine Vaped smoked dipped or snuffed or these little Zin pouches or taken in capsule form does improve cognitive performance