Alpha-GPC is a non-stimulant that can improve cognitive performance and focus, particularly in age-related cognitive decline.

“Most nootropics also include things that increase or a desire to increase acetylcholine. Things like alpha GPC and other things of that sort. And indeed, there's some evidence that they can increase acetylcholine.”

“The effects on cognitive decline are described as notable. Notable, meaning several studies showed a significant but modest effect on in offsetting cognitive decline, in particular in older populations and some populations, even with some reported neuro degeneration.”

“The one that's particularly interesting and for which there really are a lot of data is alpha GPC and I'm going to attempt to pronounce what alpha GPC actually is. It's alpha glycerylphosphorylcholine.”

“And alpha-GPC is a non-stimulant way to approach that. Again, definitely check with your doctor before taking anything or stopping to take anything, but alpha-GPC has been shown in various studies to improve cognitive performance. And in people who have age-related cognitive decline, there have been some positive benefits reported in quality, peer-reviewed journals.”

“alpha-GPC is effective in creating more focused by way of this cholinergic system, It stimulates acetylcholine release from both of those locations, the PPN in the back of the brain and nucleus basalis in the front of the brain.”

“One such compound is so-called alpha GPC, which is a form of choline and increases acetycholine transmission dosages as high as 1200 milligrams per day, which has a very high dosage spread out, typically it's 300 or 400 milligrams spread out throughout the day have been shown to offset some of the effects of age-related cognitive decline, improved cognitive functioning people that don't have age-related cognitive decline that's a very high dose. Typically when people are using alpha-GPC to study or to enhance learning of any kind, they will take somewhere between 300 and 600 milligrams that's more typical.”

“taking 300 milligrams of Alpha GPC, most certainly does increase my ability to focus.”

“Although there are people including people who are trying to offset age-related cognitive decline, that will take 300 milligrams of Alpha GPC three times a day, every day, which closely mimic some of the studies that have been done on humans, looking at offsetting age-related cognitive decline, using things like Alpha GPC.”

“but of course there are more and more approaches to increasing, not just nicotine, but acetylcholine generally in order to achieve cognitive enhancement or physical enhancement, or I should say physical performance enhancement. Some of those we talked about earlier, such as Alpha GPC.”

“Alpha GPC taken in 300 milligram form 10 to 30 minutes before a about of cognitive work or a about of physical work will increase your focus by way of increasing acetylcholine, and to some extent, increasing epinephrine as well.”

“Dosages as high as 1,200 milligrams per day, which is a very high dosage spread out. Typically, it's 300 or 400 milligrams spread out throughout the day, have been shown to offset some of the effects of age related cognitive decline, improve cognitive functioning, people that don't have age related cognitive decline.”

“Typically, when people are using alpha GPC to study or to enhance learning of any kind, they will take somewhere between 300 and 600 milligrams.”

“Not surprisingly then, drugs that increase cholineergic or acetyloline transmission will increase focus and cognition.”