Andrew Huberman· PhD
so areas like the orbital frontal cortex and the prefrontal cortex if you image these areas or study them even in a a rodent model of OCD which quite honestly these models they model aspects of OCD but OCD is a human condition you can't really model this whole condition in a in a mouse or a wrap but perhaps you can model compulsive behavior in a rat sure and pulling out their hair yeah exactly you know that's that's not necessarily obsessive compulsive disorder but that is compulsive behavior and perhaps if you can ameliorate that in a rat that might be helpful for a patient with OCD but we have to approach animal modeling of OCD thoughtfully uh and and most scientists do I think uh when we study OCD in in models or in in humans with imaging and and we're trying to do it invasively with with electrodes like we do in epilepsy patients we find that areas in the cortex like the prefrontal and orbital frontal cortex are are not functioning they will the way they would in a non-oc patient they are often hyper functioning