Peter Attia· MD
not a colleague but um a colleague in science pier medist in Switzerland has developed what he calls the asite neuron lactate shuttle and that's really sparked a lot of interest in the the metabolism of asites
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
not a colleague but um a colleague in science pier medist in Switzerland has developed what he calls the asite neuron lactate shuttle and that's really sparked a lot of interest in the the metabolism of asites
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So the glucose transporter in neurons. So if neurons are using lactate primarily...the astrocytes are actually what's... Shuttling a lot. The astrocytes are using glucose and that's why the brain needs glucose and they're producing the lactate. The neurons are using the lactate because it's getting shunted and converted into pyruvate.
neurons are actually mostly using lactate from astrocytes. Astrocytes are glycolytic. The astrocytes are these brain cells in your brain which are using glucose mostly, or using glucose to generate lactate. Lactate then gets shuttled into neurons, and the reason why neurons like that is because it's thermodynamically favorable, much like beta-hydroxybutyrate which you mentioned, BHB, because it can shunt right into the TCA cycle in the mitochondria...