To accurately evaluate social behavior changes in autism trials, evaluations should be conducted unaware of medication status to mitigate placebo response.

“you really want there's a huge Placebo response rate right and so I mean it's not a placebo response rate here but but we really would want to make sure that our evaluation of the social behavior is done unaware to the medication but you can get good safety data right so so you can have those you know 13 children who were on Placebo we can then also make sure that their blood chemistry Labs look good that their cardiograms look good right and so that also allows us to assess safety parameters in a greater number of children”