The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
when individuals who already had a high working memory span took the highest dose of bromocriptine and by the way studies verified that the amount of dopamine available indeed increased so that was important to do and they did that well their working memory performance actually decreased such that now they had a short or a low working memory span
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
so what this tells us is that the relationship between dopamine and working memory follows an inverted u-shaped function so imagine a u and then just flip it over meaning if you have low dopamine availability in the prefrontal cortex working memory span is short as you increase that amount working memory becomes greater but if you increase the amount of dopamine in the prefrontal cortex too much working memory span actually drops significantly below the Baseline that you started with
it is the case that when dopamine levels are lower that is either there are fewer neurons that have the potential to release dopamine in the frontal cortex or for whatever reason less is being released in the frontal cortex that working memory performance tends to be lower as compared to conditions where dopamine release or the availability of dopamine is higher however it is not the case that more dopamine is always going to equate to improved working memory
so there's a kind of inverted us shape function to this