Andrew Huberman· PhD
deliberate cold exposure, and cyclic hyperventilation can both cause deployment of molecules such as epinephrine and norepinephrine that lead to enhanced immune system function if done repeatedly.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
deliberate cold exposure, and cyclic hyperventilation can both cause deployment of molecules such as epinephrine and norepinephrine that lead to enhanced immune system function if done repeatedly.
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We can confidently say the molecules epinephrine and norepinephrine, which are released in both brain and body in response to cold water exposure, as well as things like deliberate hyperventilation, the release of norepinephrine and epinephrine into the brain and body is known to have a number of different effects related to the immune system. It can be pro-immune, at least in the short term.