Andrew Huberman· PhD
the best way to shut down neurons is to cool them, so there are a lot of examples of this in the scientific literature, but most people aren't aware of it because you're not digging around in the method section of these papers, but when we want to shut down neurons, we can do things like inject drugs that will do that, like lidocaine, you know, the stuff that makes you numb at the dentist, or you can use different inhibitors, but one of the best ways to do it experimentally is to just cool neurons, when you make neurons cold, because there's a temperature dependence of when neurons can be active and when they can't, the neurons shut down