Rhonda Patrick· PhD
Resistance exercise training was associated with a 45% reduction in multiple depressive symptoms according to a meta-analysis of 33 randomized controlled trials.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Resistance exercise training was associated with a 45% reduction in multiple depressive symptoms according to a meta-analysis of 33 randomized controlled trials.
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Just two 25-minute resistance training sessions per week can significantly reduce depression symptoms, with results that are more than double the effectiveness of typical antidepressants like SSRIs.
But resistance training also improves depressive symptoms.