The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So this is super interesting because what it means is that lithium is causing circuits to be less active, ketamine is causing circuits to be more active. And we know from excellent clinical data now that ketamine seems to be a very effective treatment for major depression, and for the major depressive episodes of people that suffer from bipolar depression
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
ketamine has been shown to provide relief not just for treatment resistant depression of the major depression type right there's many different forms of depression but major depression is the one that we're normally thinking about or referring to when we talk about depression but ketamine has also been shown to be effective in treating bipolar depression sometimes called bipolar disorder although more commonly nowadays called bipolar depression I did an entire episode by the way on bipolar depression if you want to know what it is and what it isn't how it differs from borderline personality disorder Etc you can go to hubman lab.com just put into the search function bipolar and it will take you to that episode ketamine has also been shown to be useful for the treatment of PTSD and for OCD obsessive compulsive disorder and for anxiety and for various forms of substance addiction