Andrew Huberman· PhD
Now, the key thing about ketamine that's often not discussed is that while its effects are very potent, they are transient. So one major drawback to ketamine therapy for depression is that it has to be done repeatedly
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Now, the key thing about ketamine that's often not discussed is that while its effects are very potent, they are transient. So one major drawback to ketamine therapy for depression is that it has to be done repeatedly
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the typical Contour is that people will take ketamine get this euphoric dreamlike dissociative effect come out of that feeling some immediate relief from their depression this is one of the things that makes ketamine an incredibly attractive drug for the treatment of depression especially depression that hasn't responded to other forms of treatment which is that people get relief very very quickly indeed the same day that they initiate the treatment