Andrew Huberman· PhD
Ketamine as a treatment for major depression seems to be effective but transient.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Ketamine as a treatment for major depression seems to be effective but transient.
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ketamine, as I'm sure you know, has been shown to actually have very significant antidepressant effects and treatment-resistant depressed patients, at least a subtype of them. Those effects are immediate. They're pretty profound but they're very short-lived.