Rhonda Patrick· PhD
Inflammatory markers are elevated in people with depression.
Loading…
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Inflammatory markers are elevated in people with depression.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
in fact the reason that depression is associated with increased inflammation is because there’s a subgroup of depressed people that have elevated inflammation, and they’re different than depressed people that don’t.
Now I thought, for many years, because I’m kind of a lumper, not a splitter, that may be what you were looking at here was that depressed people, that they’re all in inflammatory simple thing, that some depressed people just have higher inflammation, and that’s what’s doing it. And other people may be depressed because they’re more sensitive to inflammation, but that it’s all too much inflammation in one way or other, you know. We now are pretty sure that that’s not true, that in fact the reason that depression is associated with increased inflammation is because there’s a subgroup of depressed people that have elevated inflammation, and they’re different than depressed people that don’t.
they also have very different responses to immune agents than people that have lower levels of inflammation.
People that have, there’s not a cut off, but the people that have higher levels of inflammation and depressed, have different functional connectivity in their brains than people that have lower levels.