Depression is a common comorbidity in multiple sclerosis, not solely attributable to the psychological impact of paralysis.

“likewise there are certain uh neurological diseases like multiple sclerosis it turns out the incidence of depression as a comorbidity in multiple sclerosis is enormous and you might think well there's a trivial reason for that if you're paralyzed from Ms you're bummed out about life and that's the reason but if you look at people who have spinal cord injuries from accidents they actually have major depression at a at a at a rate from people who are uninjured so that doesn't seem to be it”