Rhonda Patrick· PhD
For example, pro-inflammatory cytokines injected into healthy people caused depressive symptoms compared to placebo.
Loading…
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
For example, pro-inflammatory cytokines injected into healthy people caused depressive symptoms compared to placebo.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
I found this study that was very interesting where they injected people with endotoxin caused it in caused inflammation and it caused depressive symptoms.
both the endotoxin and interferon gamma but not the placebo caused people that have an increase in circulating levels of pro-inflammatory cyto kindes including il6 and tnf Alpha as we might have expected but very interestingly in both cases they also experienced an acute increase in depressive symptoms anxiety feelings of social disconnection and a lack of reactivity to pleasure able stimuli known as anhedonia
lps in circulation also affects the way we feel so healthy individuals that are injected with lps experience symptoms of depression depressive mood feelings of social disconnection they also have elevations in inflammatory cytokines like tnf alpha il-6 compared to people that are injected with a saline control