Peter Attia· MD
And what the fructose was doing is when it went into the polyp, it was converted to fructose 1-phosphate by an enzyme called ketohexokinase, also called fructokinase. That enzyme's only found in three tissues in any significant concentration, the liver, the kidney, and the gut. And so these polyps, like the normal gut cells, have that enzyme. that has been something of a mystery of why that enzyme exists at that location. But in any event, it does. What happens is the fructose goes in, it gets phosphorylated by that enzyme, and it happens very rapidly. It's a very active enzyme. And that drops the ATP level in the cell because you're consuming ATP to phosphorylate that fructose that's coming in.