Caloric restriction in monkeys leads to a decrease in gene expression related to inflammation and stress, and an increase in gene expression related to neurotrophic factors.

“the monkey that was eating a normal diet as much food as it wanted when it wanted it was increasing the expression of bad genes genes involved in inflammation and stress and it was decreasing the expressions of good genes like neurotrophic factors which are important for the growth of new brain cells and the monkey the cowork restricted monkey had the opposite genetic expression profile so it was decreasing the bad genes it was decreasing the expression of genes involved in inflammation and stress and it was increasing the good genes”