Beta-hydroxybutyrate can influence histone acetylation, affecting gene transcription and translation.

“and so beta-hydroxybutyrate tends to do a number of different things and functions through the acetylene rate so one of the things that we study is kabuki syndrome where there is a suppression of settle a ssin of a gene and the suppression of that acetylation contributes to what is known as kabuki syndrome and it's a very rare genetic disease and we have mice from Johns Hopkins where we are looking doing the behavioral studies but also measuring those the effect of ketones on a set elation and gene transcription and translation”