David Sinclair· PhD
Among enriched pathways for smoking, they observed “Glucuronidation,” “Biological oxidations,” “Metallothioneins bind metals,” and NF-κB target gene sets, consistent with tobacco’s toxicity
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Among enriched pathways for smoking, they observed “Glucuronidation,” “Biological oxidations,” “Metallothioneins bind metals,” and NF-κB target gene sets, consistent with tobacco’s toxicity
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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