The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
as the epigenetic clock ages, we are seeing more genes that are regulating NF-kappaB turn on causing more inflammation? So, it's not necessarily the cause of aging but it's helping accelerate it as you start to accumulate these epigenetic changes, as they start to shift.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And then, in my lab, I'm just really excited to figure out what the epigenetic clocks are. We have no idea, we apply these measures to a bunch of different things, we have no idea what drives these changes or, functionally, what they even mean. So, why is your epigenetic clock related to your mortality risk? It's like what is the pathway that links those two things?
But yeah, we still don't know exactly what the CpGs that are in these clocks are functionally doing.