The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
When you took estrogen and progesterine or estrogen alone, you had a decreased risk of colon cancer. You had decreased risk of fractures, like significant decrease of fractures, decrease of diabetes. We saw a decrease in overall mortality, a decrease in cancer specific mortality.
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So, what did it show? Let's talk about the good. When you took estrogen and progesterine or estrogen alone, you had a decreased risk of colon cancer. You had decreased risk of fractures, like significant decrease of fractures. Decrease of diabetes.