Peter Attia· MD
if you want to give estrogen to a woman who still has her uterus you have to give her progesterone as well you have to be able to have a hormone to oppose the estrogen
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if you want to give estrogen to a woman who still has her uterus you have to give her progesterone as well you have to be able to have a hormone to oppose the estrogen
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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We figured out pretty quickly how to combat that. If you just oppose the estrogen with progesterone, you keep the endometrial lining in check.