Distance running, such as marathons, causes inflammation reflected in elevated Hs-CRP levels.

“the highest CRP as I've ever had were in there and I'm not sure if I've even told you what they were before I think I've heard something's never like in the 50s yeah one was 52 the highest one I had ever had”

“The time after the full marathon I had thirty-eight and outside of that yeah was no lower than a seven when it was the day following a half marathon now certainly as you know much of working out particularly when you do something like distance running is you're fully aware that you are going to be inflaming yourself that's actually just part of the process”

“thing and running a marathon is a pretty well recognized in the literature way to make your CRP level Skyrocket right and you know because you're causing damage and your body reacts to the damage in a perfectly normal way and one of those ways is to tag all these things and say we know what's going on here don't worry about it guys right so sterile information inflammation is that process basically recognizing that there's been some sort of stress on the body and it's caused some oxidative stress and you know that the body has some repair and growth regrowth to do which is perfectly healthy or it means that you've got an infection and that's non-sterile inflammation obviously which causes a lot of the same routes you know the inflammatory inflammatory response routes to be triggered so you know what we're really interested in is sterile inflammation because that seems to be the pathway that triggers all these chronic diseases where I mean it's literally like um effectively an autoimmune disease”