you have following that protein synthesis and that's that longer time frame somewhere between 12 hours there it's certainly not peaked for 48 hours it may be still there 48 hours from now but it is is absolutely coming down at that point
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
you have following that protein synthesis and that's that longer time frame somewhere between 12 hours there it's certainly not peaked for 48 hours it may be still there 48 hours from now but it is is absolutely coming down at that point
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a single resistance training bout causes this interesting cascade of things where muscle protein synthesis will peak 24 hours after the resistance training bout. And it will take as long as 48 to 72 hours to come down to baseline levels to where you had not done the resistance training bout.
but the untrained duration lasts much longer so it it's still not back to baseline in studies by 48 well some studies it's back to baseline at 48 hours in other studies there's still a statistical difference at 48 hours so we think basically in untrained people it's about 48 to 72 hour response the interesting thing is in trained people that initial robust response comes back down about 10 to 12 hours and at 24 hours is basically not different from baseline
the peak so that the change percentage is about it increases it's different from study to study but — about 100 to 150 percent increase in muscle protein synthesis that p that that peak is about the same for trained versus untrained
the myofibrillar protein synthesis they actually don't know how long it lasts because they've only assessed it up to 16 hours post and so far neither group has returned to baseline
To some extent, it also has to do with the muscle protein synthetic response, which is roughly the time course...it's about 48 hours, it can be truncated a little as you get actually more advanced, you seem to get a higher spike.