Physical activity can increase the mass of the mitochondrial network in muscle tissue.

“You mentioned training for a marathon will double the number of mitochondria >> at most.”

“if you train to run a marathon, for example, you can double the number of mitochondria in your muscles.”

“what you have is a bigger bigger Energy Delivery system that goes from the cell's surface deep within the fiber through this network again some people call it the cellular Energy power grid”

“The physical activity is known to increase the mass of the mitochondrial network. Some people would say there are more mitochondria, but we know, from our own work, that this is a whole network and the mitochondrial network buds and branches out with training. So, you can actually double the amount of mitochondria you have in your muscle by training.”

“When you exercise regularly, your muscles get bigger, and in the case of endurance muscles, better endurance. And associated with that, there's an increased number of mitochondria, healthy mitochondria, in each muscle cell. So, that makes sense. The cells then are more able to generate the ATP to support their function.”