Rhonda Patrick· PhD
When exercise volume is increased or high-intensity training is added, the so-called “non-response” disappears completely.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
When exercise volume is increased or high-intensity training is added, the so-called “non-response” disappears completely.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
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But true non-responders to exercise don’t exist. Instead, research shows that the dose just isn’t high enough for some individuals.
Now some of that non-response was eliminated in a group that was doing the same total amount of exercise but engaging in a more vigorous manner.